SINGLE-CELL CANCER SYSTEMS BIOLOGY AND PHARMACOLOGY
The Birtwistle Lab combines computational and experimental methods to understand how cancer cells make decisions. We aim to use this understanding to better predict drug and drug combination responses. We give particular focus to brain tumors, although the approaches we take are quite flexible and can be applied to a multitude of cell and cancer types. Our goal is to build simulation models that can guide patient-specific therapies by accounting for mechanisms of drug action within the unique complexity of an individual’s tumor. This goal brings with it both basic and applied science projects.
See our Research and Publications page for more detailed information. We are very thankful for current funding from the National Institutes of Health (NIGMS, NHGRI and NCI), Roche, and Glaxo-Smith-Kline.
Keep up with what's going on in the lab via our Twitter feed:
-
Congratulations to the new Dr. McCarthy! Can't wait to build on your work that showed us how to do combinatorial fl… https://t.co/aJoPsc0mdW -
RT @DoctorBou: Looking for molecular biology and virology postdocs — please consider applying! See 🧵👇🏽#virology #postdoc… https://t.co/uiQobXEnBX
-
A recent short paper from us (Arnab Mutsuddy and @cemalerdeme) addressing computational bottlenecks in large-scale… https://t.co/YzrDNs2sjo
-
Some initial ideas just out from @cemalerdeme and myself on how machine learning / big data can help to fill gaps i… https://t.co/e8HAooFMBn
-
RT @kD3AN: Blebs promote cell survival by assembling oncogenic signalling hubs, by @MuthrNaturzSon, @BusterHawthorne,… https://t.co/vqX6FXXhkP